Akademik Veri Yönetim Sistemi
6th Internation Congress of Analytical and Bioanalytical Chemistry, Antalya, Türkiye, 26 - 29 Mart 2026, ss.105, (Özet Bildiri)
Electrochemical
Determination of Bisphenol A Utilizing ErGO-Chitosan Nanocomposite Sensing Platform
Barış DOST1*, Şener SAĞLAM1, Ayşem ARDA1, Reşat APAK1,2
1Engineering
Faculty, Chemistry Department, Istanbul University−Cerrahpaşa, Avcilar,
Istanbul, Turkey
2Turkish
Academy of Sciences (TUBA), Bayraktar neighborhood, Vedat Dalokay st. No:112,
06670, Cankaya, Ankara, Turkey
*E-mail: baris.dost@iuc.edu.tr
Concerns regarding the potential adverse health effects of
endocrine-disrupting chemicals (EDCs) are on the rise. Among these, Bisphenol A
(BPA)—chemically identified as 2,2-bis(4-hydroxyphenyl) propane—serves as a
primary precursor in the synthesis of polycarbonate (PC) and epoxy resins (EP).
These materials are extensively utilized in the manufacturing of everyday items
such as water bottles, linings for food cans, and plastic containers for food
storage1. To prepare the ErGO (Electrochemical reduced graphene
oxide)-Chitosan composite electrode, the chitosan solution was mixed with a
certain volume GO (Graphene oxide) solution at a 1:1 volume ratio (v/v).
Subsequently, the resulting mixture was drop-cast onto the electrode surface
and allowed to dry at room temperature. For the electrochemical reduction step,
the modified electrode was subjected to cyclic voltammetry in 0.1 M H2SO4
within the potential range of 0 to-1.3 V. The electrochemical
measurements were carried out using Square Wave Voltammetry (SWV) with the
modified electrode in a phosphate-buffered saline (PBS) solution at neutral pH.
The anodic oxidation response was recorded within the potential range of -0.2 V
to 1.0 V. The electrochemical determination of BPA using the GCE/ErGO-Chitosan
modified electrode via SWV exhibited a well-defined characteristic oxidation
peak at approximately 0.56 V. A linear relationship was established between the
anodic peak current and BPA concentration in the range of 0.4-32 μmol L-1,
with a correlation coefficient (r) 0.998. Notably, no significant potential
shift was recorded in the peak positions despite the concentration increase.
Furthermore, the synergistic effect of the GO-Chitosan composite facilitated
sharper peak signals, thereby enhancing the detection capabilities and widening
the linear working range. In contrast to the poor adsorption observed on the
bare GCE, the ErGO-Chitosan modification yielded remarkably stable and sharp
oxidation peaks. By combining the high conductivity of reduced graphene oxide
with the molecular recognition capacity of chitosan, this platform accelerated
electron transfer, significantly enhancing both analytical sensitivity and
linear working range.
Keywords: Bisphenol A, Sensor Electrode, Nanocomposite, SWV
References
1-Yin, H., Zhou, Y., Xu, J., Ai, S., Cui, L., & Zhu, L. (2010).
Amperometric biosensor based on tyrosinase immobilized onto multiwalled carbon
nanotubes-cobalt phthalocyanine-silk fibroin film and its application to
determine bisphenol A. Analytica chimica acta, 659(1-2), 144-150.
Acknowledgment: This study was funded
by Scientific Research Projects Coordination Unit of Istanbul University -
Cerrahpasa Rectorate. Project number:38010