Research Information System
Turkish Nephrology, Dialysis and Transplantation Journal, vol.23, no.2, pp.164-168, 2014 (SCI-Expanded, ESCI, Scopus, TRDizin)
Highest prevalence of all antineutrophil cytoplasmic antibody associated systemic vasculitides is the Wegener granulomatosis, and it's typically characterized by a necrotizing granulomatous vasculitis of the respiratory tracts, kidneys, and skin. Neurologic involvement in Wegener granulomatosis ranges from 22% to 54%, but central nervous system involvement is from 2% to 8%. Cranial nerve involvement as an initial sign with concomitant systemic disease is extremely rare. Involvement of one or more cranial nerves is generally a seemingly isolated finding in Wegener granulomatosis. We present WG cases that presented with treatment-resistant cranial nerve involvement and acute fatal pulmonary-renal syndrome.