SARS-CoV-2 IgG Antibody Levels After Inactivated Vaccine (CoronaVac) among Elderly
Infectious Diseases and Clinical Microbiology, cilt.4, sa.2, ss.129-132, 2022 (ESCI, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 4 Sayı: 2
- Basım Tarihi: 2022
- Doi Numarası: 10.36519/idcm.2022.115
- Dergi Adı: Infectious Diseases and Clinical Microbiology
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.129-132
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet
Özet
We aimed to describe the antibody response against SARS-CoV-2 after inactivated COVID-19 vaccine in elderly individuals. SARS-CoV-2 IgG levels were measured in the blood samples of 126 volunteers over the age of 60. The antibody positivity rate was 42.8% after the first dose and 96.8% after the second dose of the vaccine. The median antibody titers after two vaccine doses were 561.3AU/mL and 43AU/mL, respectively(p<0.001). After vaccination, 22.2% of the participants had antibodies equivalent to 1:80 dilutions in plaque reduction neutralization test (PNRT). We believe that the booster dose is needed to continue the protective immune response in especially elderly groups.