COVID-19-associated Isolated Cortical Vein Thrombosis: Detection of SARS‐CoV‐2 in CSF


Atacan Yaşgüçlükal M.

The Neurohospitalist, vol.12, no.12, pp.520-523, 2022 (Scopus) identifier identifier identifier identifier

  • Publication Type: Article / Case Report
  • Volume: 12 Issue: 12
  • Publication Date: 2022
  • Doi Number: 10.1177/19418744221079145
  • Journal Name: The Neurohospitalist
  • Journal Indexes: Scopus
  • Page Numbers: pp.520-523
  • Istanbul University-Cerrahpasa Affiliated: No

Abstract

COVID-19 has been associated with central nervous system manifestations; however, cerebral venous thrombosis is rarely reported. A 34-year-old woman was admitted to the hospital with headache and recurrent seizures; she was recently discharged after COVID-19 pneumonia. Cranial magnetic resonance imaging and magnetic resonance venography showed cortical vein thrombosis in the right frontal lobe. SARS-CoV-2 RNA was detected in cerebrospinal fluid analysis. The patient was anticoagulated and put on antiepileptics. The most probable mechanism underlying the venous thrombosis is COVID-19-associated hypercoagulability. However, the relation between the viral RNA in cerebrospinal fluid analysis and the thrombosis is controversial.