Synthesis and characterization of some 2-quinonyl piperazine derivatives

ŞAHİNLER AYLA S., Gonul G. P.

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, cilt.197, sa.9, ss.943-951, 2022 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 197 Sayı: 9
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1080/10426507.2022.2047968
  • Dergi Adı: PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier
  • Sayfa Sayıları: ss.943-951
  • Anahtar Kelimeler: 2, 3-dichloro-1, 4-naphthoquinone, 1, 4-benzoquinone, piperazine, thiols, mass spectroscopy, NUCLEOPHILIC-SUBSTITUTION, 2,3-DICHLORO-1,4-NAPHTHOQUINONE
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

The synthesis of a series of some piperazine derivatives with quinone moiety was carried out in present study. Obtained 2-quinonyl piperazine derivatives were then reacted with some aliphatic or aromatic thiol nucleophiles and new N,S-substituted of 1,4-naphthoquinone synthesized. The structures of novel molecules were elucidated by microanalysis and spectroscopic methods such as FT-IR, H-1-NMR, C-13-NMR, UV-Vis. Mass and MS/MS fragmentation studies were also performed and fragmentation pathway of protonated novel piperazine derivatives were proposed.