The effect of halofuginone, a specific inhibitor of collagen type 1 synthesis, in the prevention of esophageal strictures related to caustic injury.

Ozcelik, MEHMET; Pekmezci, S; Saribeyoglu, K; Unal, E; Gumustas, MUSTAFA; Dogusoy, G

doi:10.1016/j.amjsurg.2003.11.008

The effect of halofuginone, a specific inhibitor of collagen type 1 synthesis, in the prevention of esophageal strictures related to caustic injury.

Ozcelik M. F., Pekmezci S., Saribeyoglu K., Unal E., Gumustas K., Dogusoy G.

American journal of surgery, cilt.187, sa.2, ss.257-60, 2004 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 187 Sayı: 2
Basım Tarihi: 2004
Doi Numarası: 10.1016/j.amjsurg.2003.11.008
Dergi Adı: American journal of surgery
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.257-60
Anahtar Kelimeler: halofuginone, caustic injury, esophagus, stricture, collagen type 1, EPIDERMAL GROWTH-FACTOR, I SYNTHESIS, LYE STRICTURES, BURNS, RAT, BOUGIENAGE, FIBROSIS, THERAPY, MODEL, VIVO
İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

Background: To assess the effects of halofuginone, a specific inhibitor of synthesis of collagen type 1, which is the major constituent of fibrosis, on esophageal stricture formation due to caustic ingestion.