Akademik Veri Yönetim Sistemi
Diagnostic and interventional imaging, cilt.98, sa.1, ss.57-61, 2017 (SCI-Expanded, Scopus)
© 2016 Editions françaises de radiologie. Published by Elsevier Masson SAS. All rights reserved.Purpose: The purpose of this study was to assess the diagnostic value of measuring the apparent diffusion coefficient (ADC) of ovarian stroma in polycystic ovary syndrome (PCOS). Materials and methods: This study was approved by the institutional review board and informed consent was obtained from each women. A total of 17 women (mean age, 22.2 years ± 5.1 [SD]; range, 1633 years) with a diagnosis of PCOS according to the Androgen Excess and PCOS Society criteria and 18 healthy women (mean age, 22.8 years ± 5.2 [SD]; range, 1631 years) who served as a control group were included in this prospective study. ADC values of the ovarian stroma during the early follicular phase were calculated by two observers in the two groups. Comparisons were performed using the Student t-test. Results: The mean ADC value in woman with PCOS (1.29 ± 0.27 × 10?3 mm2/s; range: 0.59 × 10?3 1.88 × 10?3 mm2/s) was significantly lower than that in the control group (1.48 ± 0.17 × 10?3 mm2/s; range: 1.12 × 10?3 1.86 × 10?3 mm2/s) (P < 0.001). The ADC cut-off value for the determination of PCOS with maximum accuracy was 1.38 × 10?3 mm2/s (AUC: 0.720; 95% CI: 0.597, 0.843), yielding 78% sensitivity and 62.9% specificity. Conclusion: ADC values of ovarian stroma are lower in patients with PCOS than in controlsubjects. ADC measurement of ovarian stroma in women with PCOS might help improve thediagnosis of PCOS.