Successful Management of Chronic Refractory Immune Thrombocytopenia with Laparoscopic Splenectomy in a Patient with Acute Promyelocytic Leukemia
INDIAN JOURNAL OF HEMATOLOGY AND BLOOD TRANSFUSION, cilt.29, ss.173-177, 2013 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 29
- Basım Tarihi: 2013
- Doi Numarası: 10.1007/s12288-012-0173-8
- Dergi Adı: INDIAN JOURNAL OF HEMATOLOGY AND BLOOD TRANSFUSION
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.173-177
- Anahtar Kelimeler: Immune thrombocytopenia, ITP, Splenectomy, Acute promyelocytic leukemia, APL, EFFICACY, PURPURA
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır
Özet
Acute promyelocytic leukemia (APL) is a particular type of acute myeloid leukemia with characteristic biological and clinical features, the frequent association at diagnosis of a severe hemorrhagic diathesis. Immune thrombocytopenia (ITP) is a common autoimmune disease characterized by low platelet counts and an increased risk of bleeding. Here we present a patient with the diagnosis of APL who achieved and maintained a remission with an induction consisting of idarubicin and ATRA, and then developed corticosteroid refractory ITP which is successfully treated with laparoscopic splenectomy.