Melatonin ameliorates oxidative damage in hyperglycemia-induced liver injury

Korkmaz G. G., Uzun H., Cakatay U., Aydin S.

CLINICAL AND INVESTIGATIVE MEDICINE, cilt.35, sa.6, 2012 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 6
  • Basım Tarihi: 2012
  • Dergi Adı: CLINICAL AND INVESTIGATIVE MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Purpose: Melatonin (N-acetyl-5-methoxy-tryptamine) is synthesized mainly by the pineal gland and its antioxidant properties have been demonstrated both in short and long term studies. Our aim was to clarify the effects of hyperglycemia and to administer melatonin on lipid peroxidation, protein oxidation and oxidative DNA damage in rat.