Radical Cystectomy and Organ Preservation Treatment Modalities in Muscle-invasive Bladder Cancer

KADIHASANOĞLU M., KARABAY E., AYDIN M., YÜCETAŞ U., TOKTAŞ M. G.

Istanbul Medical Journal, cilt.17, sa.2, ss.41-47, 2016 (ESCI, TRDizin) identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 17 Sayı: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5152/imj.2016.37790
  • Dergi Adı: Istanbul Medical Journal
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.41-47
  • Anahtar Kelimeler: Bladder cancer, cystectomy, chemotherapy, radiotherapy, organ-sparing treatments, QUALITY-OF-LIFE, TRANSITIONAL-CELL CARCINOMA, LYMPH-NODE DISSECTION, UROTHELIAL CARCINOMA, ILEAL CONDUIT, TRANSURETHRAL RESECTION, RADIATION-THERAPY, URINARY-DIVERSION, FOLLOW-UP, CHEMOTHERAPY
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Worldwide, bladder carcinoma is the most diagnosed cancer, and it is the most common urologic malignancy among men in Turkey. Although bladder carcinoma is diagnosed at an early stage of the disease, 100,000 patients are diagnosed with the muscle-invasive or advanced stage each year. Radical cystectomy (RC) and bilateral lymph node dissection are the gold standard treatments for muscle-invasive bladder cancer. Partial cystectomy, chemotherapy, radiotherapy, transurethral resection, and combined treatment modalities are other treatment options when RC is not suitable for patients. Oncologic outcomes, complications, effects on the quality of life, and cost of treatment change in each treatment modality. In this article, we aimed to review the treatment modalities for urinary bladder cancer such as radical surgical method and bladder-sparing modalities in light of the current literature.