Variations in systemic biomarkers of oxidative/nitrosative stress and DNA damage before and during the consequent two cycles of chemotherapy in breast cancer patients

Atukeren, PINAR; Yavuz, Berna; Soydinc, Hilal; Purisa, Sevim; Camlica, Hakan; Gumustas, MUSTAFA; Balcioglu, İbrahim

doi:10.1515/cclm.2010.249

Variations in systemic biomarkers of oxidative/nitrosative stress and DNA damage before and during the consequent two cycles of chemotherapy in breast cancer patients

Atukeren P., Yavuz B., Soydinc H. O., Purisa S., Camlica H., Gumustas M. K., ...More

CLINICAL CHEMISTRY AND LABORATORY MEDICINE, vol.48, no.10, pp.1487-1495, 2010 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 48 Issue: 10
Publication Date: 2010
Doi Number: 10.1515/cclm.2010.249
Journal Name: CLINICAL CHEMISTRY AND LABORATORY MEDICINE
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1487-1495
Istanbul University-Cerrahpasa Affiliated: No

Abstract

Background: Previous studies have suggested the importance of redox regulation in carcinogenesis. The aim of this study was to evaluate the prognostic role of altered redox homeostasis and oxidative DNA damage in patients with breast carcinoma before and during two cycles of chemotherapy.