Antibiotic Susceptibility of Bacteria Isolated From Children with Urinary Tract Infection

Creative Commons License

Yüksel Salduz Z. İ., Yigit O.

JOURNAL OF PEDIATRIC INFECTION, cilt.4, sa.4, ss.138-142, 2010 (ESCI, Scopus, TRDizin)

Özet

Objective: In this study we aimed to determine the causative agents and their antibiotic susceptibility in children with urinary tract infection. Material and Methods: Urine cultures and antibiotic suspectibility testings were evaluated retrospectively in children diagnosed with urinary tract infection between September 2006 and August 2007. Results: In total, positive urine cultures of 166 female and 31 male patients were analysed. Results were classified by paediatric age groups; Group 1, 1-24 months; group 2, 2-14 years. The most common causative agent was Escherichia coli (E. coli) (84.8% of cases) followed by Enterobacter spp. (6.1% of cases). Antibiotic resistance were detected for E. coli as 71.3% to ampicillin, 52.7% to trimethoprim-sulphamethoxazole, 37.1% to ampicillin-sulbactam, 23.4% to amoxicillin-clavulanat, 7% to cefuroximeaxetil, 6% to cefotaxim, 6% to ceftriaxone, 5.5% to cefixim, 12% to ciprofloxacin, 5.4% to gentamycine and amikacin has no resistance. It was found that resistance to empirically and frequently used trimeto-prim- sulphametoxasol and ampicillin was high. Conclusion: This state of affairs indicates the significance and necessity of performing antibiogram in the treatment of urinary infections in children, and suggests that, in cases where it is necessary to initiate empirical treatment, it is not appropriate to select trimetoprim-sulphametoxasol and Ampicillin. According to this study, it seems that in oral empirical treatment, primarily second-generation cepha-losporins and secondarily penicillin type antibiotics that are resistant to beta lactamase are the appropriate alternatives.