An investigation of nucleophilic substitution reactions of 2,3-dichloro-1,4-naphthoquinone with various nucleophilic reagents

Ibis C., Shntaif A. H., Bahar H., Ayla S.

JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, vol.80, no.6, pp.731-738, 2015 (SCI-Expanded, Scopus) identifier identifier

  • Publication Type: Article / Article
  • Volume: 80 Issue: 6
  • Publication Date: 2015
  • Doi Number: 10.2298/jsc141124021i
  • Journal Name: JOURNAL OF THE SERBIAN CHEMICAL SOCIETY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.731-738
  • Keywords: 1,4-naphthoquinone, thioethers, amine, indolylquinones, ANTIBACTERIAL, DERIVATIVES, ANTIFUNGAL
  • Istanbul University-Cerrahpasa Affiliated: No

Abstract

Novel N-, N,S- and N,O-substituted naphthoquinone compounds were prepared by the reactions of 2,3-dichloro-1,4-naphthoquinone (1) and the corresponding nucleophiles in the presence of chloroform and triethylamine or an ethanolic solution of Na2CO3. The structures of the novel naphthoquinone compounds were characterized by microanalysis, FT-IR. H-1-NMR, C-13-NMR, MS and cyclic voltammetry.