Topical alpha interferon in the treatment of oral ulcers in Behcet's syndrome: A preliminary report

HAMURYUDAN V., Yurdakul S., Serdaroglu S., Tuzun Y., Rosenkaimer F., Yazici H.

Clinical and Experimental Rheumatology, cilt.8, sa.1, ss.51-54, 1990 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8 Sayı: 1
  • Basım Tarihi: 1990
  • Dergi Adı: Clinical and Experimental Rheumatology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.51-54
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

The effect of topical recombinant interferon alfa 2c hydrogel (IFNα2C) in the aphthous lesions of the mouth in Behcet's syndrome was assessed in twenty patients in a twelve-week open trial. IFNα2C applied to the mouth for four weeks significantly reduced the number of aphthae in the post-treatment phase compared to the pretreatment and treatment phases. No side effects were recorded. Topical IFNα2C seems to be effective in the treatment of the aphthae in Behcet's syndrome.