Evaluation of apoptosis in cerebrospinal fluid of patients with severe head injury

Uzan, MUSTAFA; Erman, H.; Tanriverdi, TANER; Sanus, G.; Kafadar, ALİ; Uzun, Hafize

doi:10.1007/s00701-006-0887-1

Evaluation of apoptosis in cerebrospinal fluid of patients with severe head injury

Uzan M., Erman H., Tanriverdi T., Sanus G. Z., Kafadar A. M., Uzun H.

ACTA NEUROCHIRURGICA, cilt.148, sa.11, ss.1157-1164, 2006 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 148 Sayı: 11
Basım Tarihi: 2006
Doi Numarası: 10.1007/s00701-006-0887-1
Dergi Adı: ACTA NEUROCHIRURGICA
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1157-1164
Anahtar Kelimeler: apoptosis, bcl-2, caspase-3, sFas, programmed cell death, TRAUMATIC BRAIN-INJURY, PROGRAMMED CELL-DEATH, FAS LIGAND, DNA FRAGMENTATION, PRACTICAL SCALE, BCL-2, EXPRESSION, CASPASE-3, RATS, ACTIVATION
İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

Objective. To determine whether sFas, caspase-3, proteins which propagate apoptosis, and bcl-2, a protein which inhibits apoptosis, would be increased in cerebrospinal fluid (CSF) in patients with severe traumatic brain injury (TBI) and to examine the correlation of sFas, caspase-3, and bcl-2 with each other and with clinical variables.