Akademik Veri Yönetim Sistemi
International Journal of Dermatology, cilt.41, sa.3, ss.135-138, 2002 (SCI-Expanded, Scopus)
Background: Surgical techniques have recently been introduced for patients with vitiligo. Randomized controlled trials have not been performed. Aim: To compare the efficacy and side-effects of two surgical methods (suction blister vs. thin split-thickness graft technique) for the treatment of vitiligo. Methods: Three suction blisters, approximately 0.8 cm in diameter, made with a special tool attached to a vacuum extractor, which were converted to erosions by removal of the roots of the bullae, and one round erosion of approximately the same diameter, made using a silver knife, were created. One roof of a blister and two cutaneous thin split-thickness grafts taken from the gluteal region were transferred onto recipient vitiliginous areas; one was left alone. The results were evaluated by one non-blind and two blind observers bimonthly during the 3-month follow-up period. Results: Repigmentation rates were 25-65% in the suction blister technique and 90% in the thin split-thickness graft technique (P < 0.001). Conclusions: The thin split-thickness graft technique is superior to the suction blister technique in treating vitiligo.