Parainfectious autoimmune encephalitis related to SARS-CoV-2 infection, presented with catatonia
INTERNATIONAL JOURNAL OF PSYCHIATRY IN MEDICINE, cilt.58, sa.4, ss.403-410, 2023 (SCI-Expanded, SSCI, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 58 Sayı: 4
- Basım Tarihi: 2023
- Doi Numarası: 10.1177/00912174231161393
- Dergi Adı: INTERNATIONAL JOURNAL OF PSYCHIATRY IN MEDICINE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus, IBZ Online, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Psycinfo
- Sayfa Sayıları: ss.403-410
- Anahtar Kelimeler: SARS-CoV-2, catatonia, encephalitis, autoimmunity
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet
Özet
Objective SARS-CoV-2 infection commonly affects both the central and peripheral nervous systems. In this way, different neurological and psychiatric clinical pictures emerge. Whereas the effects of SARS-CoV-2 on neuronal structures in the short and long term are still controversial. Neurological involvement secondary to SARS-CoV-2 is heterogeneous in terms of both clinical presentation and treatment responses and prognosis. Method A case of autoimmune encephalitis developing after SARS-CoV-2 was presented. Results This case was admitted to the clinic with classical catatonia signs and encephalopathy together. The emergence of neuropsychiatric problems after the relief of SARS-CoV-2 symptoms, suggests that this picture was primarily related to immune processes. The presented case showed a good clinical response to symptomatic catatonia treatment and immune-modulatory agents and recovered both physically and cognitively without any sequelae. Conclusion In terms of clinical presentation and treatment response, SARS-CoV-2 infection may create a distinct encephalitic involvement after the infection itself by triggering some defined or not-yet-defined autoimmune pathways.