Proactive multiple cardiovascular risk factor management compared with usual care in patients with hypertension and additional risk factors: the CRUCIAL trial

Zamorano, Jose; Erdine, Serap; Pavia, Abel; Kim, Jae-Hyung; Al-Khadra, Ayman; Westergaard, Mogens; Sutradhar, Santosh; Yunis, Carla

doi:10.1185/03007995.2011.555754

Proactive multiple cardiovascular risk factor management compared with usual care in patients with hypertension and additional risk factors: the CRUCIAL trial

Zamorano J., Erdine S., Pavia A., Kim J., Al-Khadra A., Westergaard M., ...More

CURRENT MEDICAL RESEARCH AND OPINION, vol.27, no.4, pp.821-833, 2011 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 27 Issue: 4
Publication Date: 2011
Doi Number: 10.1185/03007995.2011.555754
Journal Name: CURRENT MEDICAL RESEARCH AND OPINION
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.821-833
Istanbul University-Cerrahpasa Affiliated: No

Abstract

To investigate whether a proactive multifactorial risk factor intervention strategy using single-pill amlodipine/atorvastatin (5/10, 10/10 mg) in addition to other antihypertensive and lipid-lowering therapy, as required, resulted in greater reduction in calculated Framingham 10-year coronary heart disease (CHD) risk compared with usual care (UC) after 52-weeks treatment.