Effects of SR-BI rs5888 and rs4238001 variations on hypertension

Caykara, Burcu; Alsaadoni, Hani; Pence, Halime; Pence, Sadrettin; Aydogan, Hulya; Sabancelebi, Sibel; Yildiz, AHMET

doi:10.1515/tjb-2018-0394

Effects of SR-BI rs5888 and rs4238001 variations on hypertension

Caykara B., Alsaadoni H., Pence H. H., Pence S., Aydogan H. Y., Sabancelebi S., ...More

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.44, no.4, pp.549-553, 2019 (SCI-Expanded, Scopus, TRDizin)

Publication Type: Article / Article
Volume: 44 Issue: 4
Publication Date: 2019
Doi Number: 10.1515/tjb-2018-0394
Journal Name: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Page Numbers: pp.549-553
Istanbul University-Cerrahpasa Affiliated: No

Abstract

Background: Scavenger receptor class B, type I (SR-BI), involved in reverse cholesterol pathway, is a multilipoprotein receptor and capable of binding HDL, LDL and VLDL. SR-BI may contribute to the development of hypertension due to accumulation of cholesterol in the vessel wall via transporting lipoproteins. Therefore, it was aimed to investigate the relationship between SR-BI rs5888 and rs4238001 variants in the patient with hypertension.