The Effects of St. John's Wort on Healing of Stages 1 and 2 Pressure Injuries: A Randomized Controlled Trial

Yildirim S., Kaya H., SÜZER Ö.

Journal of Wound, Ostomy and Continence Nursing, cilt.52, sa.4, ss.285-291, 2025 (SCI-Expanded, SSCI, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 52 Sayı: 4
  • Basım Tarihi: 2025
  • Doi Numarası: 10.1097/won.0000000000001200
  • Dergi Adı: Journal of Wound, Ostomy and Continence Nursing
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus, CINAHL, MEDLINE
  • Sayfa Sayıları: ss.285-291
  • Anahtar Kelimeler: Hypericum perforatum, Older adults, Pressure injury, St. John's wort, Wound care
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

PURPOSE: This purpose of this study was to evaluate the effects of topical St. John's wort (Hypericum perforatum) oil on wound healing in Stages 1 and 2 pressure injuries (PI). DESIGN: Randomized controlled trial. METHODS: The study was conducted between September 2020 and June 2021 in a nursing home in Istanbul, Turkey. The sample comprised 48 participants: 24 were randomly allocated to the intervention group and 24 individuals to the control group. The intervention was 0.9% NaCl and St. John's wort oil; 0.9% NaCl was administered to control group participants. The Pressure Ulcer Scale for Healing was used to measure wound healing. RESULTS: No significant between-group differences were found when control and intervention groups were evaluated at weeks 1, 2, 3, or 4. CONCLUSION: The findings of this randomized controlled trial revealed no difference between wound healing outcomes when St' John's wort oil was compared to saline in a group of patients. We recommend additional research using various stages and categories of PI to more fully determine the potential effects of topical St. John's wort oil on PI healing.