The role of "Integrated Pulmonary Index" monitoring during morphine-based intravenous patient-controlled analgesia administration following supratentorial craniotomies: a prospective, randomized, double-blind controlled study

Akcil E. F., Dilmen O. K., VEHID H. E., Yentur E., Tunali Y.

CURRENT MEDICAL RESEARCH AND OPINION, cilt.34, sa.11, ss.2009-2014, 2018 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 11
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1080/03007995.2018.1501352
  • Dergi Adı: CURRENT MEDICAL RESEARCH AND OPINION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2009-2014
  • Anahtar Kelimeler: Integrated pulmonary index, Morphine, Patient controlled analgesia, Supratentorial craniotomy, INDUCED RESPIRATORY DEPRESSION, OBSTRUCTIVE SLEEP-APNEA, POSTOPERATIVE PAIN, ONDANSETRON, SURGERY, EVENTS, NAUSEA, IPI
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

Objective: Morphine is commonly used in post-operative analgesia, but opioid-related respiratory depression causes a general reluctance for its use. The "Integrated Pulmonary Index" is a tool calculated from non-invasively obtained respiratory and hemodynamic parameters. The aim of this prospective, randomized, double blind, and placebo-controlled study is to determine a more safe and effective dose for morphine in patient-controlled analgesia following supratentorial craniotomy using the "Integrated Pulmonary Index".