Expression of MMP-1, MMP-9 and TIMP-2 in prostate carcinoma and their influence on prognosis and survival

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Ozden F., Saygin C., Uzunaslan D., Onal B., Durak H., Aki H.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, cilt.139, sa.8, ss.1373-1382, 2013 (SCI-Expanded, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 139 Sayı: 8
• Basım Tarihi: 2013
• Doi Numarası: 10.1007/s00432-013-1453-x
• Dergi Adı: JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.1373-1382
• Anahtar Kelimeler: Matrix metalloproteinases, Tissue inhibitors of metalloproteinase, Prostate carcinoma, Prognosis, Survival, CELL LUNG-CANCER, MATRIX METALLOPROTEINASES, TISSUE INHIBITORS, BREAST-CANCER, TUMOR MICROENVIRONMENT, PRELIMINARY EXPERIENCE, COLORECTAL-CANCER, BLADDER-CANCER, MESSENGER-RNA, MATRIX-METALLOPROTEINASE-9
• İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) participate in tumorigenesis, and their association with disease outcome is highly controversial. The present study investigates the influence of MMP-1, MMP-9 and TIMP-2 on different clinicopathologic variables and disease-free survival (DFS) of patients with prostate carcinoma.