Metal complexes with Schiff base and benzimidazolylphenol ligands with tent-butyl and methoxy groups: Structural characterization and biological evaluation
JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Basım Tarihi: 2026
- Doi Numarası: 10.2298/jsc260217028p
- Dergi Adı: JOURNAL OF THE SERBIAN CHEMICAL SOCIETY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Central & Eastern European Academic Source (CEEAS), Chemical Abstracts Core, Compendex, Directory of Open Access Journals, Academic Search Ultimate (EBSCO), Materials Science & Engineering Collection (ProQuest), Technology Collection (ProQuest)
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet
Özet
Two chelating ligands bearing tert-butyl and methoxy groups, an ONO type Schiff base (H2L1) and a benzimidazolylphenol derivative (HL2), NO type ligand, and their complexes with CoCl2, NiCl2, CuCl2, ZnCl2 and K2PdCl4 (1a-e and 2a-e, respectively) were synthesized and characterized. Various physicochemical and spectroscopic techniques were used to characterize the ligands. In addition, the crystal structure of H2L1 was determined by X-ray diffraction spectroscopy. Keto-enol tautomerism is observed in H2L1 according to spectral data. ric analysis, as well as FT-IR, fluorescence, UV-Vis and NMR (for diamagnetic complexes) spectroscopic techniques, were utilized to characterize the complexes. Then, antibacterial, antifungal and antiviral activities of the compound were investigated. Antimicrobial activities of the compounds were tested toward six bacteria and three fungi. Some of the complexes exhibited higher activity against Staphylococcus aureus, Staphylococcus epidermidis and Escherichia aureus and S. epidermidis) and 2c against S. aureus, S. epidermidis and E. coli higher activity than HL2 and the Co(II) and Cu(II) complexes of HL2 had the highest activity among the compounds, with rates of 62 and 64 %, respectively.