Effect of glurenorm on immunohistochemical changes in pancreatic β cells of rats in experimental diabetes

Koyuturk M., SAÇAN Ö., BOLKENT Ş., YANARDAĞ R.

Indian Journal of Experimental Biology, cilt.43, sa.3, ss.268-271, 2005 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 43 Sayı: 3
  • Basım Tarihi: 2005
  • Dergi Adı: Indian Journal of Experimental Biology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS
  • Sayfa Sayıları: ss.268-271
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Immunohistochemical localization of islets of Langerhans of streptozotocin (65 mg/kg, ip) induced diabetic + glurenorm (10 mg/kg, po) treated female albino rats revealed increase in number of β cells and insulin immunoreactivity of β cells. The results suggest that glurenorm can cause the stimulation of β cells of endocrine pancreas in diabetic rats.