Cerebrospinal fluid superoxide dismutase and serum malondialdehyde levels in patients with aneurysmal subarachnoid hemorrhage: preliminary results

Kaynar M. Y., Tanriverdi T., Kemerdere R., Atukeren P., Gumustas K.

NEUROLOGICAL RESEARCH, cilt.27, sa.5, ss.562-567, 2005 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 5
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1179/016164105x17288
  • Dergi Adı: NEUROLOGICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.562-567
  • Anahtar Kelimeler: aneurysm, free radical, lipid peroxidation, subarachnoid hemorrhage, superoxide dismutase, CEREBRAL VASOSPASM, LIPID-PEROXIDATION, TIRILAZAD MESYLATE, NEUROLOGICAL DEFICITS, GENE-TRANSFER, DOUBLE-BLIND, MICE, ATTENUATION, RADICALS, BRAIN
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

Objectives: Experimental studies provide evidence that oxidative damage plays a role in the development of vasospasm after aneurysmal subarachnoid hemorrhage (SAH) but data from human studies is still limited. The purpose of this study was to investigate the time course of cerebrospinal fluid (CSF) superoxide dismutase (SOD) and serum malondialdehyde (MDA) changes in patients with aneurysmal SAH.