Aggregation of lipoprotein(a) to apolipoprotein A-I underlying HDL dysfunction as a major coronary risk factor

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Onat A., Can G., MURAT S., CICEK G., ORNEK E., Yuksel H.

ANATOLIAN JOURNAL OF CARDIOLOGY, vol.13, no.6, pp.543-551, 2013 (SCI-Expanded, Scopus, TRDizin) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 6
  • Publication Date: 2013
  • Doi Number: 10.5152/akd.2013.175
  • Journal Name: ANATOLIAN JOURNAL OF CARDIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CINAHL, EMBASE, MEDLINE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.543-551
  • Keywords: Apolipoprotein A-I, apolipoprotein E, coronary heart disease, HDL dysfunction, lipoprotein(a), metabolic syndrome, regression analysis, HIGH-DENSITY-LIPOPROTEIN, METABOLIC SYNDROME, HEART-DISEASE, CARDIOVASCULAR-DISEASE, VASCULAR-DISEASE, ARTERY-DISEASE, TURKISH MEN, ATHEROSCLEROSIS, POPULATION, DEFINITION
  • Open Archive Collection: AVESIS Open Access Collection
  • Istanbul University-Cerrahpasa Affiliated: No

Abstract

Objective: Dysfunction of high-density lipoprotein (HDL) may contribute to coronary heart disease (CHD) risk. We determined whether aggregation to lipoprotein (Lp)(a) of apolipoprotein (apo) A-I underlies HDL dysfunction conferring incident CHD risk.