Turk Anesteziyoloji ve Reanimasyon, cilt.27, ss.97-101, 1999 (Scopus)
In this study, we aimed to compare the neuromuscular transmission in the orbicularis oculi and adductor pollicis muscles for defining the intubation time. After ethics committee approval and informed consent, we studied 40 ASA group I or II patients allocated randomly to one of two groups (n=20 in each). The group whose neuromuscular transmission of m. adductor pollicis was monitored, was named Control Group, and the group whose neuromuscular transmission of m. orbicularis oculi was monitored, was named Study Group. None of them were premedicated. After anaesthesia induction provided by thiopentone 5 mg/kg IV and fentanyl 1 μg/kg IV, vecuronium 0.1 mg/kg IV was administered. Neuromuscular transmission monitorization was provided by paragraph device. TOF stimulation was applied for each group. When TOF response did not occur, we accepted that the effect of nondepolarizan drug was begun and tracheal intubation was performed. Haemodynamic values such as mean arterial pressure(MAP) and heart rate(HR) were enrolled. Intubation condition were scored by scale modified from Domaoal. In statistical analysis of the data Student's - t test with the significance level of (0.05) was applied. The average time of disappearance of TOF response for m. adductor pollicis and for m. orbicularis oculi were 190±49.2 sec., 150±50.8 sec respectively (p<0.05). There was no significant difference in mean arterial pressure, heart rate, sex, age and weight specifications between two groups. In conclusion, monitoring neuromuscular transmission of m. orbicularis oculi is superior to m. adductor pollicis.