Considering huntington’s disease and neuroacanthocytosis in the differential diagnosis of senile chorea Senil kore olgusu: Ayırıcı tanıda huntington hastalığı ve nöroakantositozun yeri nedir?


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Elmali A. D., Gunduz A., Baslar Z., Ertan F. S.

Turk Noroloji Dergisi, cilt.21, sa.3, ss.119-123, 2015 (Scopus) identifier identifier

Özet

© 2015 Turkish Neurological Society. All rights reserved.Sporadic chorea that presents after the age of 50 years is called “senile chorea”. Senile chorea is a rare entity with a wide differential diagnosis list. Causes of senile chorea include vascular and metabolic diseases, adverse events related to medications, hematologic and immune system diseases, genetic and sporadic neurodegenerative syndromes, and paraneoplastic disorders. Although the most common etiologies are vascular and metabolic disorders, neuroacanthocytosis, Wilson’s and Huntington’s disease are included in the differential diagnosis. Herein, we discuss differential diagnosis and approach to late-onset chorea based on a patient whose clinical findings suggested chorea-acanthocytosis at first, but later revealed Huntington’s disease after detailed laboratory studies.