Emphysema or Bronchiectasis with Pulmonary Nodules: Impact on The Risk of Malignancy


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Gencer A., ATAHAN E., GEMİCİOĞLU B., BÖREKÇİ Ş., ÇALIŞKANER ÖZTÜRK B.

Thoracic Research and Practice, cilt.27, sa.4, ss.215-221, 2026 (ESCI, Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 4
  • Basım Tarihi: 2026
  • Doi Numarası: 10.4274/thoracrespract.2025.2025-10-10
  • Dergi Adı: Thoracic Research and Practice
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.215-221
  • Anahtar Kelimeler: lung cancer risk factors, lung cancer screening, pulmonary nodule with bronchiectasis, Pulmonary nodule with emphysema
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

OBJECTIVE: The increasing use of computed tomography (CT) has led to a significant rise in the detection of pulmonary nodules. This has resulted in more studies aimed at identifying risk factors associated with increased detection of early-stage lung cancer. The aim of this study is to investigate the effect of coexisting emphysema or bronchiectasis on the incidence of malignancy in pulmonary nodules. MATERIAL AND METHODS: The study included 212 patients with pulmonary nodules detected on CT images. They were divided into three groups based on the presence of emphysema or bronchiectasis. The effects of demographic factors and pulmonary nodule characteristics on malignancy were evaluated in these groups. RESULTS: Comparison of the incidence of malignancy in pulmonary nodules across groups showed no significant difference in the emphysema or bronchiectasis groups compared with the control group (P > 0.05). CONCLUSION: Contrary to what is frequently reported in the literature, the presence of emphysema was not found to be a risk factor for lung cancer in this study. The presence of bronchiectasis was also found not to be a risk factor; however, there are insufficient data in the literature on this point.