Akademik Veri Yönetim Sistemi
Comprehensive medicine, cilt.16, sa.1, ss.1-7, 2024 (TRDizin)
Objective: This study aimed to evaluate the relationship between lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH), depression, and quality of life (QoL). Materials and Methods: This cross-sectional study included 312 male patients over the age of 40 who were newly diagnosed with LUTS secondary to BPH between September 2019 and October 2023. LUTS, QoL, and depressive symptoms were assessed with the International Prostate Symptom Score (IPSS), short- form health survey (SF-36), and Beck Depression Inventory (BDI) questionnaires, respectively. Results: Depression was detected in 46 (15%) patients. While IPSS total score, storage and voiding subscores were found to be significantly higher in cases with depression than in those without depression, SF-36 QoL scores were significantly lower. Depressive symptoms were more severe in patients with moderate to severe LUTS (9.2±7.3 vs 6.7±6.3, p=0.011). IPSS total, voiding and storage subscores were positively correlated with BDI scores and mostly negatively correlated with QoL scores. Conclusion: This study showed that subjects with moderate to severe LUTS due to BPH had more severe depressive symptoms and a lower QoL than those who were mildly symptomatic. Increasing the severity of LUTS worsens depressive symptoms. Also, depression is associated with more severe LUTS.