Turk Jinekoloji ve Obstetrik Dernegi Dergisi, cilt.11, sa.2, ss.84-87, 2014 (Scopus, TRDizin)
Objective: To identify prognostic factors which affect the success of ectopic pregnancy treatment with a single dose of methotrexate. Material and Methods: Ninety nine patients who were admitted to Cerrahpaşa Medical Faculty, Obstetrics and Gynecology Department, between years 2000 and 2010 and treated with single-dose methotrexate were divided into two subgroups; successful and unsuccessful. Demographic, clinical and laboratory findings likely to affect the success of the treatment were compared retrospectively. Results: Single-dose methotrexate therapy was successful in 67 patients (67.6%). In the unsuccessful group, serum ß-hCG values were significantly higher than those of successful group (successful group median ß-hCG value: 819 (122-3822) mIU/mL, unsuccessful group median ß-hCG value: 3562 (642- 18.000) mIU/mL, p<0.001). Conclusion: Single-dose methotrexate therapy is effective in the initial treatment of ectopic pregnancy. It was observed that the main prognostic factor affecting the success is elevated levels of ß-hCG.