Effects of pentoxifylline on oxidative stress in rats with abdominal compartment syndrome model

Egin, Seracettin; Açıksarı, Kurtuluş; Ercan, Gulcin; Aydin, A.; Ustyol, Esra; Eser, Mediha; Tanriverdi, GAMZE; Yanar, Hakan

doi:10.1016/j.ijso.2016.09.001

Effects of pentoxifylline on oxidative stress in rats with abdominal compartment syndrome model

Egin S., Açıksarı K., Ercan G., Aydin A. F., Ustyol E. A., Eser M., ...Daha Fazla

INTERNATIONAL JOURNAL OF SURGERY OPEN, cilt.5, ss.5-10, 2016 (ESCI, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 5
Basım Tarihi: 2016
Doi Numarası: 10.1016/j.ijso.2016.09.001
Dergi Adı: INTERNATIONAL JOURNAL OF SURGERY OPEN
Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
Sayfa Sayıları: ss.5-10
Anahtar Kelimeler: Abdominal compartment syndrome, Pentoxifylline, Lung, Liver, Small bowel, Oxidative stress
İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Background: Abdominal compartment syndrome (ACS) causes severe pathology in the cardiovascular, renal and pulmonary systems. Recent studies showed that pentoxifylline (PTX) has effects on increasing tissue oxygenation, healing capillary refill and reducing superoxides and hydroxyl radicals by inhibiting xanthine oxidase. In this study, our aim was to study the effects of PTX on free oxygen radicals and oxidative damage in rats with ACS model.