Effects of pentoxifylline on oxidative stress in rats with abdominal compartment syndrome model
INTERNATIONAL JOURNAL OF SURGERY OPEN, cilt.5, ss.5-10, 2016 (ESCI, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 5
- Basım Tarihi: 2016
- Doi Numarası: 10.1016/j.ijso.2016.09.001
- Dergi Adı: INTERNATIONAL JOURNAL OF SURGERY OPEN
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
- Sayfa Sayıları: ss.5-10
- Anahtar Kelimeler: Abdominal compartment syndrome, Pentoxifylline, Lung, Liver, Small bowel, Oxidative stress
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır
Özet
Background: Abdominal compartment syndrome (ACS) causes severe pathology in the cardiovascular, renal and pulmonary systems. Recent studies showed that pentoxifylline (PTX) has effects on increasing tissue oxygenation, healing capillary refill and reducing superoxides and hydroxyl radicals by inhibiting xanthine oxidase. In this study, our aim was to study the effects of PTX on free oxygen radicals and oxidative damage in rats with ACS model.