Wide Resection Treatment of Angiomatoid Fibrous Histiocytoma in a 42-Year- Old Female
Hamidiye Medical Journal , cilt.4, sa.3, ss.194-197, 2023 (TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 4 Sayı: 3
- Basım Tarihi: 2023
- Doi Numarası: 10.4274/hamidiyemedj.galenos.50251
- Dergi Adı: Hamidiye Medical Journal
- Derginin Tarandığı İndeksler: TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.194-197
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet
Özet
Angiomatoid fibrous histiocytoma is a rare neoplasm with malignant potential that primarily occurs in the subcutaneous tissues or dermis of the extremities in children or young adults. Its characteristic histological appearance involves the nodular growth of histiocytic, epithelioid, or spindle cells surrounded by a fibrous pseudocapsule containing a lymphocytic cuff. It may also feature a prominent myxoid stroma. Unresectable or metastatic tumors may have limited treatment options. Immunotherapy using PD-1/PD-L1 inhibitors could play a role in the future, although it is not yet widely adopted. The standard surgical approach for angiomatoid fibrous histiocytoma involves wide or radical resection of the lesion. In this article, we discuss the case of a 42-year-old female patient who presented to our clinic with shoulder pain and was subsequently diagnosed with angiomatoid fibrous histiocytoma after biopsy.
Keywords: Angiomatoid fibrous histiocytoma, Pd-1/pd-l inhibitors, wide resection