The relationship between antioxidant enzymes and bladder cancer

Arikan S., Akcay T., Konukoglu D., Obek C., Kural A.

NEOPLASMA, cilt.52, sa.4, ss.314-317, 2005 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 52 Sayı: 4
  • Basım Tarihi: 2005
  • Dergi Adı: NEOPLASMA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.314-317
  • Anahtar Kelimeler: bladder cancer, free radicals, malondialdehyde, glutathione S-transferase, glutathione peroxidase, GLUTATHIONE S-TRANSFERASES, FREE-RADICALS, GASTRIC-CANCER, BLOOD, POLYMORPHISMS, PEROXIDASE, GENOTYPES, OXIDANT, PLASMA
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Carcinogenesis proceeds through at least three distinct stages - initiation, promotion and progression. Free radicals play an important role in the multistep complex course of carcinogenesis. Urinary bladder has been recognized as a target organ for many carcinogens, including benzidine, beta-napthylamine, 2 napthylamine, 4-aminobiphenyl. Antioxidants have been shown to inhibit both initiation and promotion in carcinogenesis.