Is there any relationship between adipocytokines and angiogenesis factors to address endothelial dysfunction and platelet aggregation in untreated patients with preeclampsia?

Gungor, ZEYNEP; Ekmekci, HAKAN; Tuten, ABDULLAH; Toprak, Sait; Ayaz, Gulsel; Caliskan, Oktay; Sonmez, HÜSEYİN; Madazli, RIZA; Donma, Orkide; Kucur, MİNE; Ulutin, ALİ; Ekmekci, ÖZLEM

doi:10.1007/s00404-017-4461-2

Is there any relationship between adipocytokines and angiogenesis factors to address endothelial dysfunction and platelet aggregation in untreated patients with preeclampsia?

Gungor Z. B., Ekmekci H., Tuten A., Toprak S., Ayaz G., Caliskan O., ...Daha Fazla

ARCHIVES OF GYNECOLOGY AND OBSTETRICS, cilt.296, sa.3, ss.495-502, 2017 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 296 Sayı: 3
Basım Tarihi: 2017
Doi Numarası: 10.1007/s00404-017-4461-2
Dergi Adı: ARCHIVES OF GYNECOLOGY AND OBSTETRICS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.495-502
Anahtar Kelimeler: Preeclampsia, Endoglin, Sflt-1, Leptin, vWF, Endothelial dysfunction, Platelet aggregation, VON-WILLEBRAND-FACTOR, SOLUBLE ENDOGLIN, SERUM ADIPONECTIN, NITRIC-OXIDE, P-SELECTIN, ANTIANGIOGENIC FACTORS, PLASMA ADIPONECTIN, NORMAL-PREGNANCY, LEPTIN, GHRELIN
İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Preeclampsia is a multisystem disorder and its etiology remains still unclear. Recent hypotheses rely on imbalance between angiogenic and antiangiogenic factors and disruption of endothelial function of spiral arteries. In addition; increased VTE (venous thromboembolism) risk is still unclear in preeclampsia. Our aim was to investigate the relationship between endothelial dysfunction, adipocytokines, platelet function, and vasculogenesis in preeclampsia.