Histopathological efficiency of amifostine in radiation-induced heart disease in rats

Gurses, İCLAL; Ozeren, M.; Serin, M.; Yucel, N.; Erkal, H.

doi:10.4149/bll_2018_011

Histopathological efficiency of amifostine in radiation-induced heart disease in rats

Gurses I., Ozeren M., Serin M., Yucel N., Erkal H. S.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.119, sa.1, ss.54-59, 2018 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 119 Sayı: 1
Basım Tarihi: 2018
Doi Numarası: 10.4149/bll_2018_011
Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.54-59
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

OBJECTIVE: Amifositine is a phosphorylated thiol that holds its radioprotective actions by several indirect mechanisms. The purpose of this study was to evaluate histopathologically whether amifositine administration prior to irradiation would have a long-term protective effect on heart tissue in an experimental rat model.