Evaluation of 52 cases with prenatally diagnosed mild fetal ventriculomegaly Hafif fetal ventrikülomegali prenatal tanisi olan 52 olgunun i̇rdelenmesi


Madazli R., Şal V., Saǧlam B., GEZER A., Ocak V.

Turkiye Klinikleri Jinekoloji Obstetrik, cilt.20, sa.3, ss.165-169, 2010 (Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 3
  • Basım Tarihi: 2010
  • Dergi Adı: Turkiye Klinikleri Jinekoloji Obstetrik
  • Derginin Tarandığı İndeksler: Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Veterinary Science Database
  • Sayfa Sayıları: ss.165-169
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Objective: To evaluate clinical characteristics and prognosis of prenatally diagnosed mild fetal ventriculomegaly cases. Material and Methods: A retrospective investigation of the 52 consecutive cases of mild fetal ventriculomegaly (ventriculer width between 10-15 mm) diagnosed in utero in our clinic, 2000-2009 inclusive. Gestational age at diagnosis, ventriculer width measurements, associated malformations and chromosomal anomalies and obstetric outcomes were evaluated. Results: Gestational age at diagnosis was 21.8 ± 4.6 (15-35) weeks. Associated malformations were detected in 78.7% of cases. Spina bifida, corpus callosum agenesis, Dandy Walker malformation and syndromic pathologies were encountered in 55.7%, 9.6%, 7.7% and 5.1% of cases respectively. In our series 61.5 % of the cases were medically aborted, 1.9% were lost in utero, 15.4% were lost after birth, 5.8% had developed various morbidities and 15.4% were alive and healthy. Of the 11 isolated mild ventriculomegaly cases 2 (18.2%) had medical abortion, 1 (9.1%) was lost after birth and 7 (63.6%) were alive and healthy. All isolated mild ventriculomegaly cases with ventriculer width between 10-12 mm were alive and healthy. Conclusion: Associated malformations and chromosomal anomalies adversely affect prognosis in mild fetal ventriculomegaly cases. Isolated mild ventriculomegaly cases with ventriculer width between 10-12 mm have a favourable outcome. Copyright © 2010 by Türkiye Klinikleri.