Age as a Modulator of Inflammatory Cardiovascular Risk Factors

Anuurad E., Enkhmaa B., Gungor Z., Zhang W., Tracy R. P., Pearson T. A., ...More

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, vol.31, no.9, pp.2151-2157, 2011 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 9
  • Publication Date: 2011
  • Doi Number: 10.1161/atvbaha.111.232348
  • Journal Name: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2151-2157
  • Keywords: aging, coronary artery disease, epidemiology, risk factors, C-REACTIVE PROTEIN, ACTIVATING-FACTOR ACETYLHYDROLASE, DENSITY-LIPOPROTEIN CHOLESTEROL, CORONARY-ARTERY-DISEASE, PHOSPHOLIPASE A(2), APPARENTLY HEALTHY, ATHEROSCLEROSIS, ASSOCIATION, FIBRINOGEN, MARKERS
  • Istanbul University-Cerrahpasa Affiliated: No

Abstract

Objective-Levels of acute phase reactants are affected by age. The extent to which cardiovascular risk associated with aging is due to an increase in the inflammatory burden is not known. We assessed the relationship with age of inflammatory markers, representing (1) systemic (C-reactive protein, fibrinogen, and serum amyloid-A) and (2) vascular (lipoprotein-associated phospholipase A(2) and pentraxin-3) inflammation.