Ischemia-modified albumin and advanced oxidation protein products as potential biomarkers of protein oxidation in Alzheimer's disease

Altunoglu E., GUNTAS G., Erdenen F., AKKAYA E., TOPAC I., Irmak H., ...More

GERIATRICS & GERONTOLOGY INTERNATIONAL, vol.15, no.7, pp.872-880, 2015 (SCI-Expanded, SSCI, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 7
  • Publication Date: 2015
  • Doi Number: 10.1111/ggi.12361
  • Journal Name: GERIATRICS & GERONTOLOGY INTERNATIONAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Page Numbers: pp.872-880
  • Keywords: advanced oxidation protein products, Alzheimer's disease, ischemia-modified albumin, oxidative stress, prooxidant-antioxidant balance, STRESS MARKERS, BALANCE, DAMAGE, WOMEN
  • Istanbul University-Cerrahpasa Affiliated: Yes

Abstract

BackgroundThe aim of the present study was to determine the systemic levels of oxidative stress markers, such as ischemia-modified albumin (IMA), advanced oxidation protein products (AOPP), ferric reducing antioxidant power (FRAP) and the prooxidant-antioxidant balance (PAB), to clarify protein redox homeostasis in patients with Alzheimer's disease, and to compare them with mentally healthy persons of the same age.