Fear-conditioned alterations of motor cortex excitability: The role of amygdala

Gokdemir S., Gunduz A., Ozkara Ç., Kiziltan M. E.

NEUROSCIENCE LETTERS, vol.662, pp.346-350, 2018 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 662
  • Publication Date: 2018
  • Doi Number: 10.1016/j.neulet.2017.10.059
  • Journal Name: NEUROSCIENCE LETTERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.346-350
  • Keywords: Motor evoked potential, Auditory startle response, Fear-conditioning, Amygdala, Corticospinal pathway, Reticulospinal pathway, TRANSCRANIAL MAGNETIC STIMULATION, POTENTIATED STARTLE, CENTRAL NUCLEUS, STRIA TERMINALIS, SILENT PERIOD, BED NUCLEUS, INVOLVEMENT, PATHWAY
  • Istanbul University-Cerrahpasa Affiliated: No

Abstract

Background and objective: We hypothesized that fear-conditioning may increase motor cortical excitability in preparation for response to fear. We tested our hypothesis in healthy subjects and in the second step, to determine the role of amygdala in alterations of motor cortex excitability, we included a group of patients who previously underwent unilateral amygdalo-hippocampectomy for temporal lobe epilepsy.