Antibiotic administration in targeted nanoparticles protects the faecal microbiota of mice

Borsa, Baris; Sudagidan, Mert; Aldag, Mehmet; Baris, Isik; Acar, Elif; Acuner, Cagatay; Kavruk, MURAT; Ozalp, Veli

doi:10.1039/d0md00347f

Antibiotic administration in targeted nanoparticles protects the faecal microbiota of mice

Borsa B. A., Sudagidan M., Aldag M. E., Baris I. I., Acar E. E., Acuner C., ...Daha Fazla

RSC MEDICINAL CHEMISTRY, cilt.12, sa.3, ss.380-383, 2021 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 12 Sayı: 3
Basım Tarihi: 2021
Doi Numarası: 10.1039/d0md00347f
Dergi Adı: RSC MEDICINAL CHEMISTRY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE
Sayfa Sayıları: ss.380-383
İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Antibiotic therapy comes with disturbances on human microbiota, resulting in changes of bacterial communities and thus leading to well-established health problems. In this study, we demonstrated that targeted teicoplanin administration maintains the faecal microbiota composition undisturbed in a mouse model while reaching therapeutic improvements for S. aureus infection.