Increased skin reactions with hydroxychloroquine during breast radiotherapy

Yildirim H. C., Şahin M., ENGİN B., ÇOLPAN ÖKSÜZ D.

Journal of Cancer Research and Therapeutics, cilt.19, sa.5, ss.1433-1435, 2023 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 5
  • Basım Tarihi: 2023
  • Doi Numarası: 10.4103/jcrt.jcrt_145_21
  • Dergi Adı: Journal of Cancer Research and Therapeutics
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.1433-1435
  • Anahtar Kelimeler: Hydroxychloroquine, radiosensitizer, radiotherapy
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

With the advances in radiation technology, skin reaction due to postoperative radiotherapy (RT) in breast cancer patients is generally mild and tolerable. However, certain drugs may increase the radiation effect. In literature, only few cases of adverse reactions in the radiation field have been reported with the use of Chloroquine. This report describes the case of a 30-year-old young female who had enhanced skin reactions with hydroxychloroquine (HCQ) treatment during breast RT. HCQ should be used with caution in patients undergoing RT due to its potential radiosensitizer effect.