Increased skin reactions with hydroxychloroquine during breast radiotherapy
Journal of Cancer Research and Therapeutics, vol.19, no.5, pp.1433-1435, 2023 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 19 Issue: 5
- Publication Date: 2023
- Doi Number: 10.4103/jcrt.jcrt_145_21
- Journal Name: Journal of Cancer Research and Therapeutics
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, MEDLINE, Veterinary Science Database
- Page Numbers: pp.1433-1435
- Keywords: Hydroxychloroquine, radiosensitizer, radiotherapy
- Istanbul University-Cerrahpasa Affiliated: Yes
Abstract
With the advances in radiation technology, skin reaction due to postoperative radiotherapy (RT) in breast cancer patients is generally mild and tolerable. However, certain drugs may increase the radiation effect. In literature, only few cases of adverse reactions in the radiation field have been reported with the use of Chloroquine. This report describes the case of a 30-year-old young female who had enhanced skin reactions with hydroxychloroquine (HCQ) treatment during breast RT. HCQ should be used with caution in patients undergoing RT due to its potential radiosensitizer effect.