FROM BENCH TO BEDSIDE: THE JOURNEY OF AMPS AS THERAPEUTICS
HEALTH & SCIENCE 2024-I, Hakan KAYA,Fethi YAVUZ, Editör, Efe Akademi, İstanbul, ss.147-167, 2024
- Yayın Türü: Kitapta Bölüm / Araştırma Kitabı
- Basım Tarihi: 2024
- Yayınevi: Efe Akademi
- Basıldığı Şehir: İstanbul
- Sayfa Sayıları: ss.147-167
- Editörler: Hakan KAYA,Fethi YAVUZ, Editör
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet
Özet
Antimicrobial peptides (AMPs) are compounds that play an important role in innate immunity. These molecules are tiny (< 10 kDa)(Zaslof, 2002) with 40-60 amino acids and several basic residues including arginine, lysine, and histidine. These peptides have a diverse method of action and show broadspectrum antibacterial effectiveness against a variety of pathogens, including bacteria, fungi, viruses, and even certain parasites. Plants, insects, amphibians, and mammals all manufacture AMPs as a natural defensive mechanism. This defensive mechanism demonstrates their evolutionary significance in battling microbial illnesses (Bahar and Ren, 2013).