Novel nanoparticle-based colorimetric probes and sensors for determining phenolic antioxidants, biothiols, nitrite and hydrogen peroxide

Apak R., Ercag E., Ozyurek M., Guclu K., Uzer A., Celik S. E., ...More

26th Anniversary World Congress on Biosensors (Biosensors), Gothenburg, Sweden, 25 - 27 May 2016, vol.27, pp.94-95, (Full Text) identifier

  • Publication Type: Conference Paper / Full Text
  • Volume: 27
  • Doi Number: 10.1016/j.protcy.2017.04.040
  • City: Gothenburg
  • Country: Sweden
  • Page Numbers: pp.94-95
  • Istanbul University-Cerrahpasa Affiliated: Yes

Abstract

This study examines the principles and milestones of nanoparticle (NP)-based colorimetric sensors and probes developed by our research group. A novel method for antioxidant capacity estimation was developed on the polyphenol-mediated growth of Ag-NPs and optical monitoring of the corresponding plasmon absorption bands. A new optical sensor using Ellman's reagent-adsorbed gold nanoparticles in colloidal solution was devised to selectively determine biothiols. Nitrite was determined by means of 4-aminothiophenol-modified Au-NPs and naphthylethylene diamine as coupling agent. Hydrogen peroxide was detected with the use of Fe3O4 magnetite NPs as peroxidase-like catalyst using a N,N-dimethyl-p-phenylenediamine (DMPD) probe. (C) 2017 The Authors. Published by Elsevier Ltd.