Renal "hyperfiltrators" are at elevated risk of death and chronic diseases

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Altay S., Onat A., OZPAMUK-KARADENIZ F., KARADENIZ Y., KEMALOGLU-OZ T., Can G.

BMC NEPHROLOGY, vol.15, 2014 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15
  • Publication Date: 2014
  • Doi Number: 10.1186/1471-2369-15-160
  • Journal Name: BMC NEPHROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: Autoimmune activation, Cardiovascular disease, Chronic obstructive pulmonary disease, Glomerular filtration rate, Heart failure, Renal hyperfiltration, GLOMERULAR-FILTRATION-RATE, IMPAIRED FASTING GLUCOSE, SERUM URIC-ACID, FOLLOW-UP, DIABETIC-NEPHROPATHY, INSULIN-RESISTANCE, METABOLIC SYNDROME, ALL-CAUSE, STATE, MEN
  • Open Archive Collection: AVESIS Open Access Collection
  • Istanbul University-Cerrahpasa Affiliated: No

Abstract

Background: The definition of glomerular hyperfiltration has not been agreed upon and the pathophysiological mechanisms have not been well explored. Low serum creatinine concentrations may be associated with increased risk of coronary heart disease (CHD) or cardiopulmonary events the impact of which needs further study.