Akademik Veri Yönetim Sistemi
REVISTA CIENTIFICA-FACULTAD DE CIENCIAS VETERINARIAS, cilt.35, sa.3, 2025 (SCI-Expanded, Scopus)
Adipokins regulat energy ohmesasis. High-ft Wstern methoate DMT) pe ticide i one of the c emicals used todit leadsto obesity and disruptsadipocytemetabolism. otecsomagriculturaaresfromharmfulorgnismsDMT Probiotics such as Lactobacillus rhamnosus GG are effective sidues re eased directly or ndirectly to the envi onment in obesity management. This study investigates the effect of irT ihuse serious problems n natu e DM residues m xed w th t e Lactobacillus rhamnosus GG on serum adipokine levels in rats quaticenvironmentderselffectaticorganismsd fed a High-fat Western diet. Thirty 5-6 week old male Wistar a ya qua an albino rats (Rattus norvegicus domestica)were randomly iseffetiscarriedtohumansthough thefod chan.Inthis iiudy,oxidativestressrsposesinduced bDMTpsticden selected and divided into three groups: control (standard tchow), W (45% fat), and a were WLgroup inves tigated. supplemented For this orally purpose, with Lacobacillurhamnosus GG in vegetable oil for 16 weeks. At s idative stres and antiox dant parameters Th iob arb tur ic ac idtheend of the study, blood samples were collected from rats via actvesubstances(TBARS)Glutathione(GSH)Superoxide smutase (SOD)catalase(CAT)andglutathioneperoxidase cardiac puncture, and serum adipokine levels were measured using ELISA kits. Body weight, naso-anal length, and BMI (body PX) d b odimeth ate DMT) icide in mass index) exhibited statistically significant increases in the cause y ( pestWgroup. In the Lactobacillus rhamnosus GG-supplemented 71.5,35and 70mgL1 concentrationsa24and 96hours ree invest g ate. Results were de ermined u sing ELISA kits. group (WL), bod y weight and BMI decreased, while naso-anal iillength increased. SFRP5 and CT1 levels were low, and asprosin and vaspin levels were high in the Wgroup. CT1, vaspin, and Sciiereobse ved between decreases in CAT nd GPx ctivitieand asprosin levels increased in the Lactobacillus rhamnosus GGa-creases in TBARS leve s SPSS 24 0 p ckage program one way supplemented group. In conclusion, Lactobacillus rhamnosus ucn e voocemcaNOVA (Dna 005)was usedin th ealuatinfboh il GG alleviates obesity, increases naso-anal length, and reduces BMI in rats fed a High-fat Western diet. These results suggest that L. rhamnosus may regulate serum CT1, vaspin, and alyz s As a result, it was d termined that DMT ca ed oxidative .ress formationin andcasedchngesinenzyme asprosin levels, but not omentin or SFRP5 in the High-fat Westrn diet model etivities .