Akademik Veri Yönetim Sistemi
FDI Annual World Dental Congress, İstanbul, Türkiye, 28 - 31 Ağustos 2013, ss.189, (Özet Bildiri)
Introduction: Casein phosphopeptide (CPP) plays a role in stabilizing and localizing amorphous calcium phosphate (ACP) on the tooth surface. CPP can rebuild subsurface areas of enamel defects, however little is known about the effects of CPP in orthodontic patients on periodontal disease. Aim: The aim of this randomized controlled clinical trial is to evaluate the effects of Tooth Mousse’s (CPP-ACP) on periodontal parameters, inflamation parameters and the saliva and GCF levels of IL-1 b, osteoprotogerin and RANKL in patients undergoing orthodontic treatment. Method: The study population consisted of fourty patients aged between 13 and 17 years with fixed appliances and ethics approvalhas been granted. First scaling was performed and oral hygiene introduction were given. After 1 month unstimulated saliva and GCF samples were collected from the incisors and canine teeth. Plaque Index, Gingival Index, Bleeding on Probing, Probing Depth, Bonded Bracket Index, DKK were carried out. Patients were randomly assigned to test group or the control group. Tooth Mousse were given only to the test group. One month after the examination, at the second visit all clinical indices were repeated. Results: At the first visit GCF level of IL-1 b and PD scores, at the second visit PD were significantly higher in the test group. There is statistically significant difference in GCF Osteoprotogerin, BOP, BBI, GI scores between first and second visit in the test group, and saliva RANKL scores in the control group (p = 0.05). Conclussion: In this observational study, CCP-ACP was associated with periodontal clinical parameters in patients undergoing orthodontic treatment. The results of this analysis should be confirmed in other observational studies.