G protein beta 3 subunit gene polymorphism in Turkish hypertensives


Alioglu E., Ercan E., Tengiz I., Yildiz A. , Tuerk U. O. , Saygi S., ...More

ANATOLIAN JOURNAL OF CARDIOLOGY, vol.8, no.5, pp.331-335, 2008 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 5
  • Publication Date: 2008
  • Title of Journal : ANATOLIAN JOURNAL OF CARDIOLOGY
  • Page Numbers: pp.331-335

Abstract

Objective: G protein is one of the most important regulators of intracellular signaling pathways. C825T polymorphism of G protein (33 subunit is associated with increased intracellular signal transduction. The 825T allele has been found associated with a variety of cardiovascular risk factors, including hypertension. The aim of the present study was to investigate the association between the C825T polymorphism of the G protein beta 3 subunit and essential hypertension in Turkish population.