Antioxidant Supplementation in Childhood Obesity: A Path to Improved Metabolic Health?

Lupu A., Mihai C. M., Dragan F., Tarnita I., Alecsa M., Chisnoiu T., ...Daha Fazla

Antioxidants, cilt.14, sa.4, 2025 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 14 Sayı: 4
  • Basım Tarihi: 2025
  • Doi Numarası: 10.3390/antiox14040466
  • Dergi Adı: Antioxidants
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Chemical Abstracts Core, Food Science & Technology Abstracts, Directory of Open Access Journals
  • Anahtar Kelimeler: antioxidants, children, obesity, oxidative stress, supplementation
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

Childhood obesity is linked to heightened oxidative stress, a key driver of endothelial dysfunction, inflammation, and metabolic complications. Antioxidants, including Vitamins C and E, are vital in neutralizing free radicals and mitigating oxidative damage. This non-systematic review examines the potential advantages of antioxidant supplementation in pediatric obesity, focusing on its effects on vascular health, insulin sensitivity, and inflammatory processes. Emerging data suggest that antioxidants may improve endothelial function, reduce blood pressure, and enhance metabolic homeostasis in obese children. However, the long-term efficacy and safety of antioxidant supplementation remain uncertain, necessitating further rigorous randomized controlled trials. A deeper understanding of antioxidants’ role in pediatric obesity could unlock novel therapeutic approaches for managing obesity-related complications and improving children’s overall health outcomes.