Dietary curcumin and capsaicin: Relationship with hepatic oxidative stress and apoptosis in rats fed a high fat diet

Creative Commons License

Tanrıkulu-Küçük S., Basaran-Kucukgergin C., Söğüt İ., Tunçdemir M., Dogru-Abbasoglu S., Seyithanoğlu M., ...Daha Fazla

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, cilt.28, ss.1013-1020, 2019 (SCI-Expanded, Scopus)

Özet

Background. Apoptosis plays a major role in fatty liver disease. High-fat diets are related to the onset of fatty liver disease and hepatic oxidant-antioxidant imbalance. Curcumin and capsaicin are somewhat beneficial in reducing hepatic triglycerides; this is most likely because they are known to downregulate reactive oxygen species (ROS) and apoptosis.